Smooth muscle spasms
Adult: 30-60 mg tid.
Parenteral
Smooth muscle spasms
Adult: 7.5-15 mg, given 2-4 times daily via IM/IV/SC inj.
Rectal
Smooth muscle spasms
Adult: 60 mg 3-4 times daily.
Indications and Dosage
Oral
Smooth muscle spasms Adult: 30-60 mg tid. Parenteral Smooth muscle spasms Adult: 7.5-15 mg, given 2-4 times daily via IM/IV/SC inj. Rectal Smooth muscle spasms Adult: 60 mg 3-4 times daily.
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Contraindications
Glaucoma, micturition disorders due to prostatic hypertrophy; severe heart disease; paralytic ileus.
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Special Precautions
Prostatic hypertrophy, hyperthyroidism, CHF, arrhythmia, ulcerative colitis or those exposed to high environmental temperature. May impair ability to drive or operate machinery. Pregnancy.
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Adverse Reactions
Visual accommodation disturbance; vertigo; thirst, constipation; palpitation; rash or other symptoms of hypersensitivity; micturition difficulties.
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Drug Interactions
Action potentiated by tricyclic antidepressants (TCAs), phenothiazines and MAOIs.
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Action
Description:
Mechanism of Action: Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract, and has a spasmolytic action. |
MIMS Class
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